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Summary of Boerhaavia diffusa

Boerhaavia diffusa is an herb found in Ayurveda and other traditional medicines. Historically, Boerhaavia diffusa has been used for its anti-diabetic and diuretic properties. In different areas of the world, Boerhaavia diffusa has also been used for pain relief, anti-inflammation, and treating indigestion. Boerhaavia diffusa is a tropical crawling root plant, with bioactive compounds in both the leaves and roots.

There have not been any human studies conducted on Boerhaavia diffusa, but animal evidence suggests it is an effective diuretic, and can suppress the proliferation of immune cells. This can be harmful in some cases, like during flu season, but beneficial if the immune system is hyperactive. Boerhaavia diffusa also has an anti-proliferative effect on some cancer cells, which means it prevents them from spreading. This anti-cancer effect comes from the isolated bioactive purnavarine. Boerhaavia diffusa also has anti-oxidant properties.

Boerhaavia diffusa's anti-inflammatory and anti-oxidative mechanisms are plausible explanations for Boerhaavia diffusa's potent anti-diabetic effects, which rivals the potency of standard drugs like Glibenclamide and Metformin. Further research is needed to confirm this relationship.

The standard Boerhaavia diffusa dose used in rat studies is in the range of 200-400mg/kg, with a maximally effective dose of 1000mg/kg. This translates to a human dosage of 32-64mg/kg, or:

These are estimated doses based off of animal research. There have not been any human studies conducted on Boerhaavia diffusa.